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Friday, July 24, 2020 | History

2 edition of Cyclic nucleotide metabolism. found in the catalog.

Cyclic nucleotide metabolism.

Joseph Larner

Cyclic nucleotide metabolism.

by Joseph Larner

  • 66 Want to read
  • 6 Currently reading

Published by Upjohn in Kalamazoo, Mich .
Written in English


Edition Notes

SeriesCurrent concepts
ContributionsUpjohn Company.
The Physical Object
Pagination52p. ;
Number of Pages52
ID Numbers
Open LibraryOL13834607M

The book systematizes literature data and the results of in-house research in toxicology of inorganic phosphates and fluorides. It shows the modes of action of a yellow and red phosphorus, phosphine, hydrogen fluoride, and a number of other compounds of phosphorus and fluorine on protein metabolism, lipid metabolism, and carbohydrate metabolism, as well as bone :// Get this from a library! Cyclic-nucleotide phosphodiesterases in the central nervous system: from biology to drug discovery. [Nicholas J Brandon; Anthony R West;] -- This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe

This book explores the broad and diverse biological and physiological impacts of established and newly discovered cyclic di-nucleotide second messenger signaling systems, while also providing descriptions of the intriguing biochemical characteristics of multiple turnover enzymes and ://   Search for a Physiological Role of Cyclic GMP Metabolism in the Photoreceptors V. Cyclic Nucleotides Localization and Roles of Cyclic Nucleotide Systems in Retina Cyclic Nucleotides in Rod- and Cone-dominant Retinas VI. Biochemical and Pharmacological Approaches to Study the Entire Retina

For more than four decades, the cyclic nucleotides cyclic AMP (cAMP) and cyclic GMP (cGMP) have been recognized as important signaling molecules within cells. Under normal physiological conditions, cyclic nucleotides regulate a myriad of biological processes such as cell growth and adhesion, energy homeostasis, neuronal signaling, and muscle relaxation. In addition, altered cyclic nucleotide Cyclic nucleotide PDEs exist in multiple molecular forms (Stoclet et al., ; Loughney & Ferguson, ) and at least four different subtypes have been shown to coexist in the heart muscle (Shahid & Nicholson, ; Bode et al., ; Dubois et al., ; Taira et al., ; Engels et al., ; Kostic et al. ): (1) a Ca 2


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Cyclic nucleotide metabolism by Joseph Larner Download PDF EPUB FB2

Abstract. This chapter deals with the enzymes that synthesize and degrade cyclic nucleotides in the central nervous system. The actions of the cyclic nucleotides themselves were reviewed in OCLC Number: Notes: A Scope publication. Description: 52 pages: black and white illustrations ; 23 cm: Contents: Introduction: historical background, page 5 --Biochemistry, page 9 --Hormone and Neurohormone action, page 16 --The prostaglandins and their interactions with Cyclic nucleotides, page 23 --Growth, cell differentiation, and cancer, page 26 --Muscular contraction and the The discovery of cyclic AMP by RALL and SUTHERLAND (see RALL, Vol.

I) led to biochemical investigations of many different receptors (including ALQUIST'S beta-adrenoceptor) that share a cyclic nucleotide as a common factor in the biochemical mechanisms that translate the occupancy of receptors into physiological :// Barber R., Butcher R.W.

() Cyclic Nucleotide Metabolism in Whole Cells. In: Swillens S., Dumont J.E. (eds) Cell Regulation by Intracellular Signals. NATO Advanced Study Institutes Series (Series A: Life Sciences), vol This book discusses the biological significance and biochemical aspects of cyclic nucleotides and protein phosphorylation in cell regulation.

The general aspects of cyclic nucleotide metabolism and action; cyclic nucleotides and nervous system; and cyclic nucleotides in muscle tissues are also :// This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy.

Specifically, this text discusses the pharmacology of calcium homeostasis and presents lectures given in the symposium. The role of cyclic nucleotides in the regulation of muscular tissue functions and the evaluation of cyclic AMP and cyclic GMP Cyclic nucleotide metabolism.

book also looked :// Jastorff B, The effects of cyclic nucleotide derivatives on cell metabolism. In: Cell Regulation by Intracellular Signals. Dumont E and Swillens S (eds), pp. –, Plenum Press, New Parker C.W. () Cyclic Nucleotide Metabolism of Reticuloendothelial Cells.

In: Reichard S.M., Escobar M.R., Friedman H. (eds) The Reticuloendothelial System in Health and Disease. Advances in Experimental Medicine and Biology, vol Given the significant role of cyclic nucleotides in signal-transduction pathways, it is not surprising that their metabolism and synthesis is highly regulated.

Such metabolism is achieved by a large number of enzymes, the phosphodiesterases (PDE), which catalyze the conversion of cAMP and cGMP into 5′-AMP and 5′-GMP, respectively, via hydrolysis of the 3′-phosphoester bonds (Fig.

This book provides a state-of-the art overview on microbial cyclic di-nucleotide signaling with a focus on cyclic di-nucleotide turnover, receptor recognition, and how these second messengers influence important aspects of the bacterial  › Life Sciences › Microbiology.

Cyclic nucleotides are intimately involved in the consequences of either stimulation or blockade of receptors; therefore, an understanding of the biochemistry of cyclic nucleotides ought to be important for pharmacologists.

Pharmacology is a science that among other things investigates  › Biomedical Sciences › Pharmacology & Toxicology. MODULATION OF CYCLIC NUCLEOTIDE METABOLISM BY ANTIPSYCHOTICS THROUGH A NON-DOPAMINE RECEPTOR Benjamin Weiss, Robert M. Levin and Louise H. Greenberg Dept. of Pharmacol., Med.

Col. of Pa., Phi la., Pa. 1 9 1 2 9 ABSTRACT Several antipsychotics of diverse chemical structure selectively bind to the endog enous calcium-dependent protein activator   reviews cyclic nucleotide metabolism in normal and proliferating epidermis in about 35 pages with references.

The first half of the review de­ scribes the basic nature of the epidermal adenyl (or Vol. 64, No.3 Printed in U.S.A. guanyl) cyclase system and the second half the cyclic nucleotides and psoriasis. The first half is(15)/pdf. In studies of the kinetic properties of photoreceptor phosphodiesterase, light was found to increase the V max but not the Km with either cAMP or cGMP as substrates.

cGMP is a preferred substrate since the Kms for cGMP and cAMP are mM and 8mM respectively ().At cyclic nucleotide concentrations of 10 −7 M the ratio of rates of hydrolysis for cGMP and cAMP respectively is greater The purpose of the present volume, the first of two on the pharmacology, biochemistry, and physiology of cyclic nucleotides, is to provide a comprehensive and up-to-date anthology on the nature and role of these important chemical regulators.

Each of the chapters is the work of  › Biomedical Sciences › Pharmacology & Toxicology. This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy. Specifically, this text discusses the pharmacology of calcium homeostasis and presents lectures given in the symposium.

The role of cyclic nucleotides in the regulation of muscular tissue functions and the evaluation of cyclic AMP and cyclic GMP are also looked :// Physiology and Pharmacology of Organ Systems The Role of Cyclic Nucleotides in the Nervous System The Role of Cyclic Nucleotide Metabolism in the Eye The Role of Cyclic Nucleotides in the Control of Anterior Pituitary Gland Activity MediaObject\/a>, schema:Book\/a> ; \u00A0\u00A0\u00A0\n library:oclcnum\/a book and appears to be free cyclic nucleotide der Stoffwechsel von Dopamin und von cGMP im Hirnstamm und im Kleinhirn gestrt central metabolism of dopamine, serotonin, cyclic AMP '_5'-Nucleotides_Mechanism.

Read "Advances in Cyclic Nucleotide Research, Volume 1. Physiology and Pharmacology of Cyclic AMP, pp. Volume 2. New Assay Methods for Cyclic Nucleotides, pp. Paul Greengard and G. Alan Robison, Series Eds. Raven Press, 15 West 84th St., New YorK, N.Clinical Chemistry" on DeepDyve, the largest online rental service for scholarly research with thousands of academic   Examination of rod outer segment preparations reveals very high levels of endogenous cyclic GMP (Fletcher and Chader, ; Krishna et al., ), implying that perhaps much of this cyclic nucleotide is in the outer segment of photoreceptor support of this idea is the finding that in retinas devoid of photoreceptor cells from mice with an inherited retinal degenerative disease, levels.

A key enzyme for the synthesis of one nucleotide is dihydrofolate reductase (right). Cells grown in the presence of methotrexate, a reductase inhibitor, respond by increasing the number of copies of the reductase gene. The bright yellow regions visible on three of the chromosomes in the fluorescence micrograph (left), which were grown in the presence of methotrexate, contain hundreds of copies Sodium uptake from the soil is a major cause of salinity toxicity in plants, yet little is known about the mechanisms that underlie Na+ influx.

We have characterized voltage independent channels (VICs) in Arabidopsis roots that are thought to contribute to Na+ entry. VICs showed no selectivity among monovalent cations, and their gating was found to be voltage   Purchase Cell Physiology Source Book - 4th Edition.

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